Obesity in the father – increased risk of cancer in the daughter

Obesity in the father – increased risk of cancer in the daughter

This study is groundbreaking because it’s the first to look into how a dad’s obesity could impact his kids’ risk of cancer. Turns out, being overweight can mess with a man’s sperm DNA, which can have serious implications for his daughter’s health before she’s even born.

So, how does it work? Well, excess weight can change the tiny regulators in cells called micro-RNAs, which control how genes are expressed. And these changes aren’t just happening in Dad’s sperm but also in his daughter’s breast tissue. It’s like passing down a genetic message that says, “Hey, watch out for cancer!”

You might have heard that obesity tends to run in families, just like certain types of breast cancer. Moms who are overweight during pregnancy often have bigger babies who also face a higher risk of breast cancer later in life.

This study, published in Scientific Reports, suggests that these tiny micro-RNAs could be carrying information from overweight dads to their daughters, making them more susceptible to breast cancer down the line. It’s like a genetic hand-me-down that nobody wants!

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