STDs are a serious health problem affecting millions of people. Symptoms of an STD vary depending on the specific disease, including rashes, burning when urinating, unusual stools, and more. Undetected sexually transmitted infections can lead to serious consequences such as infertility, development of cancer and others. Fortunately, many of them can be treated with antibiotics or other methods. Regular preventive examinations and safe sexual practice are essential to maintain health and prevent the spread of sexually transmitted infections. Both men and women are at risk of contracting sexually transmitted diseases, and the incidence may vary depending on various factors such as sexual activity, methods of protection used, etc. For example, for some infections such as chlamydia, women are more often affected, while for others, such as gonorrhea or syphilis, the risk may be equal between the sexes. However, regular testing and protective measures such as condom use can reduce the risk of contracting and spreading STDs. Women have a greater biological risk of contracting sexually transmitted infections and HIV than men, particularly because of their more vulnerable reproductive systems. Data from the Centers for Disease Control and Prevention shows that in 2020, chlamydia and gonorrhea infections were more common among females aged 10-19 than among males. Young people aged 15-24 are particularly vulnerable, with girls at greater risk due to biological and social factors. Transgender people are also at increased risk of sexually transmitted infections due to biological and social reasons. It is not clear which gender has a greater risk of contracting a sexually transmitted infection because many factors play a role, such as the level of sexual activity and the type of contact. Research shows that risky behaviors such as unprotected sex, sex with multiple partners, and sharing needles increase the risk. Over 20 million new cases are reported annually in the US, with young people particularly affected. Practicing safe sex and getting tested regularly can reduce the risk of STDs. Sexual health is essential for everyone, and prevention of sexually transmitted infections is an important part of this care. Whether male or female, precautions such as condom use and regular check-ups are crucial. Many STDs can be successfully treated, but it is important to catch them early. Social and biological factors play a role in increasing risk, but with the right approach, their impact can be reduced.