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Sexually transmitted infections in women increase the risk of infertility
Sexually transmitted infections in women are associated with an increased risk of death and the development of other diseases, including urethritis, pelvic inflammatory disease, amniotic fluid infection, and the risk of preterm birth in pregnancy. Pelvic inflammatory disease involves infection and inflammation of the upper parts of the female reproductive system – the endometrium, fallopian…
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Ovulation – how to interpret the change in temperature?
The temperature curve is an easy and affordable way to determine the date of ovulation, in order to establish the period in which fertilization can take place and thus increase the chances of pregnancy. Interpretation of the curve The presence of a thermal rise with a plateau in the second part of the cycle confirms…
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A genetic cause of asthenozoospermia in men has been discovered
Mutations in certain genes in men lead to the infertility seen in the disease asthenozoospermia. They are the reason why the sperms are damaged and cannot move efficiently towards the eggs. The condition asthenozoospermia is characterized by reduced sperm motility, which significantly reduces male fertility. Many factors can affect male infertility, including age, nutrition and…
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Oxidative stress is a leading cause of male infertility
Oxidative stress has long been known to be associated with reproductive health disorders in men. It leads to reduced sperm motility and damage to their genetic information. This causes an increased risk of repeated abortions due to fertilization disorders and genetic abnormalities. The generation of free radicals is a natural process and is necessary for…
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Do thyroid hormones affect reproductive health?
Thyroid hormones are vital for normal female reproductive function. L-thyroxine (T4) and L-triiodothyronine (T3) act directly on ovarian, uterine and placental tissues through specific nuclear receptors that modulate the development and metabolism of these organs. In addition, they act indirectly through multiple interactions with other hormones and growth factors, such as estrogen, prolactin, and insulin-like…
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Common genetic causes of male infertility
Infertility is a multifactorial problem affecting approximately 15% of couples of reproductive age. This disorder affects approximately 7% of men. Like other multifactorial diseases, environmental factors as well as genetic and/or epigenetic (circumstances that cause certain genes to turn on and off) abnormalities are responsible for cases of male infertility, making it very difficult to…
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Low testosterone levels are a cause of male infertility
Impaired function of the testicles – hypogonadism can be the result of primary congenital disorders in the structure and function of the testicles – hypergonadotropic hypogonadism or appear as a consequence of hypothalamus and pituitary dysfunction – hypogonadotropic hypogonadism. The latter can be congenital or acquired. Acquired hypogonidism is due to: Taking psychoactive substances; Infiltrative…
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Low testosterone levels and impaired semen composition in men
A number of conditions can cause oligozoospermia – a low concentration of sperm in the seminal fluid. The hypothalamus produces and secretes gonadotropin-releasing hormone – GnRH, which reaches the anterior lobe of the pituitary gland and stimulates gonadotrope cells to release luteinizing hormone – LH and follicle-stimulating hormone – FSH into the systemic circulation. LH…
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Impaired sperm motility and shape: causes and prevention
Oligoasthenoteratozoospermia is a quantitative and qualitative disorder of the seminal fluid, which has a direct impact on the chances of fertilization. Various tests are needed to diagnose this disorder in the quality and quantity of seminal fluid. It is of prime importance to assess the quality: this is done through a spermogram, which allows to…