Cellulite is a condition characterized by the appearance of bumps on the skin, as a result of which it resembles an orange peel. Most often, cellulite appears on the thighs, stomach and glutes. In some cases, it can also appear on the chest, lower abdomen and upper arms. Cellulite occurs in 85-98% of women after puberty, while it is rare in men. The condition occurs as a result of irregular movement of the fibrous ligaments that connect the skin to the muscles underneath. As a result of the accumulation of fat, some fibrous threads are pressed against the skin, while others are pulled in the opposite direction, which is the reason for the irregularities on it. In men, the condition is usually seen with a deficiency of male hormones. Compared to men, fat in women is more densely distributed in the thighs, buttocks and hips, where cellulite is most likely to appear. In addition, women produce more estrogen during pregnancy and adolescence, which experts say stimulates the formation of cellulite. Hormones play an important role in the formation of cellulite. As estrogen levels drop, usually as women approach menopause, the receptors in the blood vessels of the thighs decrease. As a result, circulation is reduced, less oxygen and nutrients reach the area, therefore collagen production is also reduced. Fat cells, on the other hand, become larger and begin to protrude from the collagen, appearing as the bumps characteristic of cellulite. In addition to estrogen, other hormones including insulin, adrenaline, norepinephrine, thyroid hormone, and prolactin could contribute to the development of cellulite. An increase in body weight can also lead to an increase in cellulite. However, it can also be seen in weaker people. Cellulite is more likely to appear with age as the skin gradually loses its elasticity. According to some studies, there is also a genetic nox to the risk of cellulite – mutations in the angiotensin-converting enzyme (ACE) gene. Stress can also cause an increase in the levels of the catecholamines adrenaline and noradrenaline, which are thought to be involved in the development of cellulite. A high-calorie diet including carbohydrates, fats, food preservatives and salt is another factor that can contribute to the development of cellulite.